Earlier Publications

  

2005
Csanady L, Seto-Young D, Chan KW, Cenciarelli C, Angel BB, Qin J, McLachlin DT, Krutchinsky AN, Chait BT, Nairn AC, Gadsby DC. Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA. J Gen Physiol. 125(2):171-86. 2005.

Zhang X.,; Krutchinsky, A.N.; Fukuda, A.; Chen Wei, Yamamura S.; Chait, B.T and Roeder G.R. MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. Mol. Cell. Jul 1;19(1):89-100, 2005

2004
Ye JZ, Hockemeyer D, Krutchinsky AN, Loayza D, Hooper SM, Chait BT, de Lange T. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev. 18(14):1649-1654, 2004.

Ye JZ, Donigian JR, Van Overbeek M, Loayza D, Luo Y, Krutchinsky AN, Chait BT, De Lange T. TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J Biol Chem. 279(45):47264-71, 2004.

Chang EJ, Archambault V, McLachlin DT, Krutchinsky AN, Chait BT. Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry. Anal Chem. 76(15):4472-83, 2004

2003
Su, I.H.; Basavaraj, A.; Krutchinsky, A..N.; Hobert, O.; Ullrich, A.; Chait, B.T.; Tarakhovsky, A. Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat. Immunol. 4(2): 124-131, 2003.

Zhang, W.; Krutchinsky, A.N.; Chait, B.T. ”De Novo” Peptide Sequencing by MALDI-Quadrupole-Ion Trap Mass Spectrometry: A Preliminary Study J. Am. Soc. Mass Spectrom. 14(9): 1012-21, 2003.

2002
Kato, H.; Tjernberg, A.; Zhang, W.; Krutchinsky, A.N.; An, W.; Takeuchi, T.; Ohtsuki, Y.; Sugano, S.; Chait, B.T. and Roeder, R.G SYT associates with human SNF/SWI complex and C-terminal region of its fusion partner SSX1 targets histones J. Biol. Chem. 277(7): 5498-5505, 2002.

Krutchinsky, A.N. and Chait, B.T . On the Nature of the Chemical Noise in MALDI Mass Spectra J. Am. Soc. Mass Spectrom. 13(2), 129-134, 2002.

Cronshaw, J.M.; Krutchinsky, A.N.; Zhang, W.; Chait, B.T. and Matunis, M.J. Proteomic analysis of the mammalian nuclear pore complex. J. Cell Biol. 158(5): 915-927, 2002.

2001
Yang, C.Y.; Wang, J.; Krutchinsky, A.N.; Chait, B.T.; Morrisett, J.D.; Smith, C.V. Selective oxidation in vitro by myeloperoxidase of the N-terminal amine in apolipopritein B-100 J. Lipid Res. 42(11): 1891-1896, 2001.

Krutchinsky, A.N.; Kalkum, M.; Chait, B.T. Automatic Identification of Proteins with a MALDI-Quadrupole Ion Trap Mass Spectrometer. Anal. Chem. 73: 5066-5077, 2001.

2000
Loboda, A.V.; Krutchinsky A.N.; Loboda, O.; McNabb J.; Spicer V.; Ens W.; Standing K.G. Novel Linac II electrode geometry for creating an axial field in a multipole ion guide. European J. Mass Spectrom. 6 (6): 531-536, 2000.

Loboda, A.V.; Krutchinsky, A.N.; Brominski, M.; Ens, W.; Standing, K.G. A tandem Quadrupole/Time-of-Flight Mass Spectrometer with a Matrix-Assisted Laser Desorption/Ionization Source: Design and Performance. Rapid Commun. Mass Spectrom. 14(12): 1047-1057, 2000.

Krutchinsky, A.N.; Zhang, W.; Chait, B.T. Rapidly Switchable MALDI and Electrospray Quadrupole-Time-of-Flight Mass Spectrometry for Protein Identification, J. Am Soc Mass Spectrom. 11(6): 493-504, 2000.

Krutchinsky, A.N.; Ayed, A.; Donald, L.J.; Ens, W.; Duckwort, H.W.; Standing, K.G. Studies of Noncovalent Complexes in an Electrospray Ionization/ Time-of-Flight Mass Spectrometer, in Methods in Molecular Biology, vol. 146: Mass Spectrometry of Proteins and Peptides, Edited by Chapman J.R., Humana Press Inc, Totowa, NJ, June 2000, ISBN: 0-89603-609-X.

1999
Zhang, Z.; Krutchinsky, A.; Endicott, S.; Realini, C.; Rechsteiner, M.; Standing, K.G. Proteasome activator 11S REG or PA28: recombinant REG alpha/REG beta hetero-oligomers are heptamers. Biochemistry. 38(17): 5651-5658, 1999.

Yao, Y.; Huang, L.; Krutchinsky, A.; Wong, M.L.; Standing, K.G.; Burlingame, A.L.; Wang, C.C. Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei. J Biol. Chem. 274(48): 33921-33930, 1999.

Faull, K.F.; Whitelegge, J.P.; Higginson, J.; To, T.; Johnson, J.; Krutchinsky, A.N.; Standing, K.G.; Waring, A.J.; Stevens, R.L.; Fluharty, C.B.; Fluharty, A.L. Cerebroside sulfate activator protein (Saposin B): chromatographic and electrospray mass spectrometric properties. J. Mass Spectrom. 34(10): 1040-1054, 1999.

Krutchinsky A.N.; Chernushevich, I.V.; Loboda, A.V.; Ens, W.; Standing, K.G. Measurements of Protein Structure and Noncovalent Interactions by Time-of-Flight Mass Spectrometry With Orthogonal Ion Injection”, in Mass Spectrometry in Biology and Medicine, pp 17-30, Edited by Burlingame A.L.; Carr, S.A.; Baldwin, M.A.; Humana Press Inc, Totowa, NJ, September 1999, ISBN: 0-89603-799-1

1998
McComb, M.E.; Krutchinsky, A.N.; Ens, E.W.; Standing, K.G.; Perreault, H. Sensitive high-resolution analysis of biological molecules by capillary zone electrophoresis coupled with reflecting time-of-flight mass spectrometry, J. Chromatography A 800: 1-11, 1998.

Ayed, A.; Krutchinsky, A.N.; Ens, W.; Standing, K.G.; Duckworth, H.W. Quantitative evaluation of Protein-Protein and Ligand-Protein Equilibria of a Large Allosteric Enzyme by Electrospray Ionization Time-of-Flight Mass Spectrometry, Rapid Comm. Mass Spectrom. 12: 339-344, 1998.

Krutchinsky, A.N.; Chernushevich, I.V.; Spicer, V.L.; Ens, W.; Standing, K.G. A Collisional Damping Interface for an Electrospray Ionization Time-of-Flight Mass Spectrometer, J. Am. Soc. Mass Spectrom. 9: 569-579, 1998.

Krutchinsky, A.N.; Loboda, A.V.; Spicer, V.L.; Ens, W.; Standing, K.G. Orthogonal Injection of MALDI Ions into a Time-of-Flight Spectrometer Through a Collisional Damping Interface, Rapid Comm. Mass Spectrom. 12: 508-518, 1998.

Ayed, A.; Krutchinsky, A.N.; Chernushevich, I.V.; Ens, E.W.; Duckworth, H.W.; Standing, K.G. Observation of Noncovalent Complexes of Citrate Synthase and NADH by ESI/TOF Mass Spectrometry. In New Methods for the Study of Biomolecular Complexes, W. Ens et al. (eds); NATO ASI Series, Series C: Mathematical and Physical Sciences Vol. 510; Kluwer Academic Publishers, Dordrecht, 1998, pp. 135-139

1995
Krutchinsky, A. N.; Dolgin, A. I.; Utsal, O.G.; Khodorkovski, M.A. Thin-layer Chromatography/Laser desorption of Peptides Followed by Multiphoton Ionization Time-of-Flight Mass Spectrometry, J. Mass Spectrom. 30: 375-379, 1995.

Krutchinsky, A. N.; Dolgin, A. I. and Khodorkovski, M.A. Matrix-Assisted Laser Desorption of Neutral Clusters Composed of Matrix and Analyte Molecules, Anal.Chem. 67(13): 1963-67, 1995.

1991
Elokhin, V. A.; Krutchinsky, A. N.; Ryabov, S.E. The Resonantly Enhanced Two-Photon Ionization of Tryptophan Molecules in Beams Formed by Laser Evaporation of Aqueous Cryogenic Matrix, Rapid Comm. Mass Spectrom 6: 257-259, 1991.

1990
Krutchinsky, A. N.; Ryabov, S.E. Vibrational Cooling of Aniline Molecules by Laser Evaporation from Cryogenic Matrix, Chem. Phys. Lett. 170: 193-196, 1990.